| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-STEAP4/Dudulin4 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx. 50-55kDa band observed in Human Adipose lysates (calculated MW of 52.0kDa according to NP_078912.2). In transfected HEK293 transiently expressing Human Dudulin4 a band of approx |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
STEAP4 |
| Gene ID: |
79689 |
| Uniprot ID: |
STEA4_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_078912.2 |
| Immunogen Sequence: |
CVDNTLTRIRQGWERN |
| Function | Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. |
| Protein Name | Metalloreductase Steap4Six-Transmembrane Epithelial Antigen Of Prostate 4Sixtransmembrane Protein Of Prostate 2Tumor Necrosis Factor - Alpha-Induced Protein 9 |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneEarly Endosome Membrane |
| Alternative Antibody Names | Anti-Metalloreductase Steap4 antibodyAnti-Six-Transmembrane Epithelial Antigen Of Prostate 4 antibodyAnti-Sixtransmembrane Protein Of Prostate 2 antibodyAnti-Tumor Necrosis Factor - Alpha-Induced Protein 9 antibodyAnti-STEAP4 antibodyAnti-STAMP2 antibodyAnti-TNFAIP9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
