| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STEAP1 |
| Gene ID: | 26872 |
| Uniprot ID: | STEA1_HUMAN |
| Immunogen Region: | 1-80 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human STEAP1 (NP_036581.1). |
| Immunogen Sequence: | MESRKDITNQEELWKMKPRR NLEEDDYLHKDTGETSMLKR PVLLHLHQTAHADEFDCPSE LQHTQELFPQWHLPIKIAAI |
| Tissue Specificity | Ubiquitously expressed. Highly expressed in prostate tumors. |
| Function | Does not function as a metalloreductase due to the absence of binding sites for the electron-donating substrate NADPH. Promotes Fe(3+) reduction when fused to the NADPH-binding domain of STEAP4. |
| Protein Name | Steap1 ProteinSix-Transmembrane Epithelial Antigen Of Prostate 1 |
| Cellular Localisation | Endosome MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Steap1 Protein antibodyAnti-Six-Transmembrane Epithelial Antigen Of Prostate 1 antibodyAnti-STEAP1 antibodyAnti-PRSS24 antibodyAnti-STEAP antibody |
Information sourced from Uniprot.org