Anti-STAU1 antibody (478-577) [S8MR] (STJ11102118)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Staufen (478-577) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S8MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STAU1 |
| Gene ID | 6780 |
| Uniprot ID | STAU1_HUMAN |
| Immunogen Region | 478-577 |
| Immunogen Sequence | SGHVPHGPLTRPSEQLDYLS RVQGFQVEYKDFPKNNKNEF VSLINCSSQPPLISHGIGKD VESCHDMAALNILKLLSELD QQSTEMPRTGNGPMSVCGRC |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 478-577 of human Staufen (O95793). |
Additional Info
| Tissue Specificity | Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta. |
| Function | Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site. (Microbial infection) Plays a role in virus particles production of many viruses including of HIV-1, HERV-K, ebola virus and influenza virus. Acts by interacting with various viral proteins involved in particle budding process. |
| Protein Name | Double-Stranded Rna-Binding Protein Staufen Homolog 1 |
| Database Links | |
| Cellular Localisation | CytoplasmRough Endoplasmic ReticulumLocalizes Exclusively With The Rough Endoplasmic Reticulum (Rer) |
| Alternative Antibody Names | Anti-Double-Stranded Rna-Binding Protein Staufen Homolog 1 antibodyAnti-STAU1 antibodyAnti-STAU antibody |
Information sourced from Uniprot.org