Anti-STAT6 antibody [EP325] (STJ16101442)

Anti-STAT6 antibody [EP325] (STJ16101442)

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STJ16101442-1
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Short Description :Rabbit monoclonal anti-STAT6 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :EP325
Isotype:IgG
Conjugation:Unconjugated
Dilution Range:IHC-P 1:25-1:100
Formulation:Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Gene Symbol:STAT6
Gene ID:6778
Uniprot ID:STAT6_HUMAN
Post Translational Modifications Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4. Tyrosine phosphorylated following stimulation by IL3/interleukin-3. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. Mono-ADP-ribosylated by PARP14.
Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.
Protein Name Signal Transducer And Activator Of Transcription 6
Il-4 Stat
Database Links Reactome: R-HSA-186763
Reactome: R-HSA-3249367
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Nucleus
Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names Anti-Signal Transducer And Activator Of Transcription 6 antibody
Anti-Il-4 Stat antibody
Anti-STAT6 antibody

Information sourced from Uniprot.org

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