| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ST6GAL1 |
| Gene ID: | 6480 |
| Uniprot ID: | SIAT1_HUMAN |
| Immunogen Region: | 27-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-200 of human ST6GAL1 (NP_775323.1). |
| Immunogen Sequence: | KEKKKGSYYDSFKLQTKEFQ VLKSLGKLAMGSDSQSVSSS STQDPHRGRQTLGSLRGLAK AKPEASFQVWNKDSSSKNLI PRLQKIWKNYLSMNKYKVSY KGPGPGIKFSAEALRCHLRD HVNVSMVEVTDFPFNTSEWE GYLPKESIRTKAGPWGRCAV VSSAGSLKSSQLGR |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme. N-glycosylated. |
| Function | Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. |
| Protein Name | Beta-Galactoside Alpha-2 -6-Sialyltransferase 1Alpha 2 -6-St 1B-Cell Antigen Cd75Cmp-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2 -6-Sialyltransferase 1St6gal ISt6galiSialyltransferase 1 |
| Database Links | Reactome: R-HSA-4085001Reactome: R-HSA-9683673Reactome: R-HSA-9694548Reactome: R-HSA-9694719Reactome: R-HSA-975577Reactome: R-HSA-977068 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecretedMembrane-Bound Form In Trans Cisternae Of GolgiSecreted Into The Body Fluid |
| Alternative Antibody Names | Anti-Beta-Galactoside Alpha-2 -6-Sialyltransferase 1 antibodyAnti-Alpha 2 -6-St 1 antibodyAnti-B-Cell Antigen Cd75 antibodyAnti-Cmp-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2 -6-Sialyltransferase 1 antibodyAnti-St6gal I antibodyAnti-St6gali antibodyAnti-Sialyltransferase 1 antibodyAnti-ST6GAL1 antibodyAnti-SIAT1 antibody |
Information sourced from Uniprot.org
