| Function | Transfers the sialyl residue from CMP-N-acetyl-beta-neuraminate to the terminal galactose residue on sugar chains of glycoproteins and glycolipids. It's alpha-2,3-sialyltransferase activity is specific toward type II glycan chains (Galbeta1-4GlcNAc) on glycoproteins and glycolipids such as neolactosides nLc4Cer and nLc6Cer, whose sialyl-products serve as precursors for the Lewis X antigen. Critically involved in the synthesis of functional selectin ligands needed for neutrophil recruitment during inflammation and lymphocyte homing to the lymph nodes. |
| Protein Name | Type 2 Lactosamine Alpha-2 -3-SialyltransferaseCmp-Neuac -Beta-Galactoside Alpha-2 -3-Sialyltransferase ViSt3gal ViSt3galviSialyltransferase 10 |
| Database Links | Reactome: R-HSA-1912420Reactome: R-HSA-2022854Reactome: R-HSA-4085001Reactome: R-HSA-9037629 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Type 2 Lactosamine Alpha-2 -3-Sialyltransferase antibodyAnti-Cmp-Neuac -Beta-Galactoside Alpha-2 -3-Sialyltransferase Vi antibodyAnti-St3gal Vi antibodyAnti-St3galvi antibodyAnti-Sialyltransferase 10 antibodyAnti-ST3GAL6 antibodyAnti-SIAT10 antibody |
Information sourced from Uniprot.org
