| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Type 2 lactosamine alpha-2, 3-sialyltransferase is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ST3GAL6 |
| Gene ID: |
10402 |
| Uniprot ID: |
SIA10_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ST3GAL6 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human ST3GAL6 |
| Function | Transfers the sialyl residue from CMP-N-acetyl-beta-neuraminate to the terminal galactose residue on sugar chains of glycoproteins and glycolipids. It's alpha-2,3-sialyltransferase activity is specific toward type II glycan chains (Galbeta1-4GlcNAc) on glycoproteins and glycolipids such as neolactosides nLc4Cer and nLc6Cer, whose sialyl-products serve as precursors for the Lewis X antigen. Critically involved in the synthesis of functional selectin ligands needed for neutrophil recruitment during inflammation and lymphocyte homing to the lymph nodes. |
| Protein Name | Type 2 Lactosamine Alpha-2 -3-SialyltransferaseCmp-Neuac -Beta-Galactoside Alpha-2 -3-Sialyltransferase ViSt3gal ViSt3galviSialyltransferase 10 |
| Database Links | Reactome: R-HSA-1912420Reactome: R-HSA-2022854Reactome: R-HSA-4085001Reactome: R-HSA-9037629 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Type 2 Lactosamine Alpha-2 -3-Sialyltransferase antibodyAnti-Cmp-Neuac -Beta-Galactoside Alpha-2 -3-Sialyltransferase Vi antibodyAnti-St3gal Vi antibodyAnti-St3galvi antibodyAnti-Sialyltransferase 10 antibodyAnti-ST3GAL6 antibodyAnti-SIAT10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
