Anti-ST3GAL5 antibody (157-207 aa) (STJ196032)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SIAT9 at the amino acid range 157-207
General Information
| Short Description | Rabbit polyclonal anti-Lactosylceramide alpha-2, 3-sialyltransferase (157-207 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ST3GAL5 |
| Gene ID | 8869 |
| Uniprot ID | SIAT9_HUMAN |
| Immunogen | Synthesized peptide derived from the human SIAT9 at the amino acid range 157-207 |
| Immunogen Region | 157-207 aa |
| Specificity | This antibody detects endogenous levels of SIAT9 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesis, development, and oncogenesis). Mainly involved in the biosynthesis of ganglioside GM3 but can also use different glycolipids as substrate acceptors such as D-galactosylceramide (GalCer), asialo-GM2 (GA2) and asialo-GM1 (GA1), although less preferentially than beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer (LacCer). |
| Protein Name | Lactosylceramide Alpha-2 -3-SialyltransferaseCmp-Neuac -Lactosylceramide Alpha-2 -3-SialyltransferaseGm3 SynthaseGanglioside Gm3 SynthaseSt3gal VSt3galvSialyltransferase 9 |
| Database Links | Reactome: R-HSA-4085001Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Lactosylceramide Alpha-2 -3-Sialyltransferase antibodyAnti-Cmp-Neuac -Lactosylceramide Alpha-2 -3-Sialyltransferase antibodyAnti-Gm3 Synthase antibodyAnti-Ganglioside Gm3 Synthase antibodyAnti-St3gal V antibodyAnti-St3galv antibodyAnti-Sialyltransferase 9 antibodyAnti-ST3GAL5 antibodyAnti-SIAT9 antibodyAnti-UNQ2510 antibodyAnti-PRO5998 antibody |
Information sourced from Uniprot.org