| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ST3GAL3 |
| Gene ID: | 6487 |
| Uniprot ID: | SIAT6_HUMAN |
| Immunogen Region: | 30-375 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-375 of human ST3GAL3 (NP_006270.1). |
| Immunogen Sequence: | LHLLQWEEDSNSVVLSFDSA GQTLGSEYDRLGFLLNLDSK LPAELATKYANFSEGACKPG YASALMTAIFPRFSKPAPMF LDDSFRKWARIREFVPPFGI KGQDNLIKAILSVTKEYRLT PALDSLRCRRCIIVGNGGVL ANKSLGSRIDDYDIVVRLNS APVKGFEKDVGSKTTLRITY PEGAMQRPEQYERDSLFVLA GFKWQDFKWLKYIVYKERVS ASDGFWKSVATRVPKEPPE |
| Tissue Specificity | Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc. |
| Protein Name | Cmp-N-Acetylneuraminate-Beta-1 -4-Galactoside Alpha-2 -3-SialyltransferaseBeta-Galactoside Alpha-2 -3-Sialyltransferase 3Alpha 2 -3-St 3Gal Beta-1 -3(4 Glcnac Alpha-2 -3 SialyltransferaseN-Acetyllactosaminide Alpha-2 -3-SialyltransferaseSt3gal IiiSt3galiiiSt3nSialyltransferase 6 |
| Database Links | Reactome: R-HSA-1912420Reactome: R-HSA-2022854Reactome: R-HSA-3656243Reactome: R-HSA-4085001Reactome: R-HSA-9037629Reactome: R-HSA-9683673Reactome: R-HSA-9694548Reactome: R-HSA-9694719Reactome: R-HSA-977068Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecretedMembrane-Bound Form In Trans Cisternae Of GolgiSecreted Into The Body Fluid |
| Alternative Antibody Names | Anti-Cmp-N-Acetylneuraminate-Beta-1 -4-Galactoside Alpha-2 -3-Sialyltransferase antibodyAnti-Beta-Galactoside Alpha-2 -3-Sialyltransferase 3 antibodyAnti-Alpha 2 -3-St 3 antibodyAnti-Gal Beta-1 -3(4 Glcnac Alpha-2 -3 Sialyltransferase antibodyAnti-N-Acetyllactosaminide Alpha-2 -3-Sialyltransferase antibodyAnti-St3gal Iii antibodyAnti-St3galiii antibodyAnti-St3n antibodyAnti-Sialyltransferase 6 antibodyAnti-ST3GAL3 antibodyAnti-SIAT6 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and PRMT6 knockout (KO) 293T cells, using [KO Validated] PRMT6 Rabbit polyclonal antibody (STJ110124) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/88451/355635/STJ110124_1__38401.1713116745.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PRMT6 knockout (KO) 293T cells, using [KO Validated] PRMT6 Rabbit polyclonal antibody (STJ110124) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
