| Host: |
Mouse |
| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-ST2 is suitable for use in ELISA research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
10206 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Purification: |
Greater than 95% purity |
| Concentration: |
5.0 mg/ml (+/-10 %) |
| Storage Instruction: |
12 months from manufacturing at 2–8°C. Temperature analysis:-70 °C, 21 days Not Determined (N/D)-20 °C, 14 days OK +4 °C, 14 days OK +35 °C, 14 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer. |
| Association Rate Constant: |
2.1 x 106 1/Ms |
| Determination Method: |
SPR analysis (ProteOn XPR36) |
| Immunoreactivity: |
80–120 % compared to the reference sample in an FIA test |
| Tissue Specificity | Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism. In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols. |
| Protein Name | Sulfotransferase 2a1St2a1Bile Salt SulfotransferaseDehydroepiandrosterone SulfotransferaseDhea-StDhea-St8Hydroxysteroid SulfotransferaseHstSt2Sult2a3 |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-1989781Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sulfotransferase 2a1 antibodyAnti-St2a1 antibodyAnti-Bile Salt Sulfotransferase antibodyAnti-Dehydroepiandrosterone Sulfotransferase antibodyAnti-Dhea-St antibodyAnti-Dhea-St8 antibodyAnti-Hydroxysteroid Sulfotransferase antibodyAnti-Hst antibodyAnti-St2 antibodyAnti-Sult2a3 antibodyAnti-SULT2A1 antibodyAnti-HST antibodyAnti-STD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
