Anti-ST2 antibody [10201] (STJ400210)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenRecognizes both free sST2 and sST2 bound to IL-33
General Information
| Short Description | Mouse monoclonal anti-ST2 for use in CLIA and FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | CLIA/FIA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 10201 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 5.0 mg/ml (+/-10 %) |
| Formulation | 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Storage Instruction | Store at 2–8 °C, and do not freeze. |
Target Information
| Immunogen | Recognizes both free sST2 and sST2 bound to IL-33 |
| Specificity | Antibody recognizes human soluble ST2. Not determined |
Additional Info
| Tissue Specificity | Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism. In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols. |
| Protein Name | Sulfotransferase 2a1St2a1Bile Salt SulfotransferaseDehydroepiandrosterone SulfotransferaseDhea-StDhea-St8Hydroxysteroid SulfotransferaseHstSt2Sult2a3 |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-1989781Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sulfotransferase 2a1 antibodyAnti-St2a1 antibodyAnti-Bile Salt Sulfotransferase antibodyAnti-Dehydroepiandrosterone Sulfotransferase antibodyAnti-Dhea-St antibodyAnti-Dhea-St8 antibodyAnti-Hydroxysteroid Sulfotransferase antibodyAnti-Hst antibodyAnti-St2 antibodyAnti-Sult2a3 antibodyAnti-SULT2A1 antibodyAnti-HST antibodyAnti-STD antibody |
Information sourced from Uniprot.org