| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-HSC70 Interacting Protein HIP (270-369) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S6MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ST13 |
| Gene ID: |
6767 |
| Uniprot ID: |
F10A1_HUMAN |
| Immunogen Region: |
270-369 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 270-369 of human Hsc70-interacting protein (HIP) (P50502). |
| Immunogen Sequence: |
MDPRKVNELRAFVKMCKQDP SVLHTEEMRFLREWVESMGG KVPPATQKAKSEENTKEEKP DSKKVEEDLKADEPSSEESD LEIDKEGVIEPDTDAPQEMG DENAEITEEMMDQANDKKVA AIEALNDGELQKAIDLFTDA IKLNPRLAILYAKRASVFVK LQKPNAAIRDCDRAIEINPD SAQPYKWRGKAHRLLGHWEE AAHDLALACKLDYDEDASAM LKEVQPRAQKIAEHRRKYE |
| Function | One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins. |
| Protein Name | Hsc70-Interacting ProteinHipAging-Associated Protein 2Progesterone Receptor-Associated P48 ProteinProtein Fam10a1Putative Tumor Suppressor St13Renal Carcinoma Antigen Ny-Ren-33Suppression Of Tumorigenicity 13 Protein |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Hsc70-Interacting Protein antibodyAnti-Hip antibodyAnti-Aging-Associated Protein 2 antibodyAnti-Progesterone Receptor-Associated P48 Protein antibodyAnti-Protein Fam10a1 antibodyAnti-Putative Tumor Suppressor St13 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-33 antibodyAnti-Suppression Of Tumorigenicity 13 Protein antibodyAnti-ST13 antibodyAnti-AAG2 antibodyAnti-FAM10A1 antibodyAnti-HIP antibodyAnti-SNC6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
