Anti-SSX-SS18 antibody [ZR463] (STJ180683)

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STJ180683
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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal SSX-SS18 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : ZR463
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: L1RE1Uniprot ID=LORF1_HUMAN"
Specificity: Positive Control: Synovial sarcoma
Immunogen: Synthesized SS18-SSX fusion protein
Post Translational Modifications Polyubiquitinated, probably by UBR2, which induces its degradation.
Function Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.
Protein Name Line-1 Retrotransposable Element Orf1 Protein
L1orf1p
Line Retrotransposable Element 1
Line1 Retrotransposable Element 1
Cellular Localisation Nucleus
Nucleolus
Cytoplasm
Cytoplasmic Ribonucleoprotein Granule
Stress Granule
Colocalizes With Its Encoding Rna In Cytoplasmic Ribonucleoprotein Particle
Mainly Cytoplasmic
Rarely Detected In The Nucleus
Possibly Within The Nucleolus
Alternative Antibody Names Anti-Line-1 Retrotransposable Element Orf1 Protein antibody
Anti-L1orf1p antibody
Anti-Line Retrotransposable Element 1 antibody
Anti-Line1 Retrotransposable Element 1 antibody
Anti-L1RE1 antibody
Anti-LRE1 antibody

Information sourced from Uniprot.org