• Western blot analysis of lysates from HUVEC and HeLa cells, using MtSSB Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of A549 cells, using MtSSB Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using MtSSB Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using SSBP1 Polyclonal Antibody

Anti-SSBP1 antibody (99-148 aa) (STJ95791)

SKU:
STJ95791

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Single-stranded DNA-binding protein, mitochondrial (99-148 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SSBP1
Gene ID: 6742
Uniprot ID: SSBP_HUMAN
Immunogen Region: 99-148 aa
Specificity: SSBP1 Polyclonal Antibody detects endogenous levels of SSBP1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human MtSSB at the amino acid range 99-148
Function Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA). In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays a crucial role during mtDNA replication by stimulating the activity of the replisome components POLG and TWNK at the replication fork. Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity. In addition it is able to promote the 5'-3' unwinding activity of the mtDNA helicase TWNK. May also function in mtDNA repair.
Protein Name Single-Stranded Dna-Binding Protein - Mitochondrial
Mt-Ssb
Mtssb
Pwp1-Interacting Protein 17
Database Links Reactome: R-HSA-2151201
Cellular Localisation Mitochondrion
Mitochondrion Matrix
Mitochondrion Nucleoid
Alternative Antibody Names Anti-Single-Stranded Dna-Binding Protein - Mitochondrial antibody
Anti-Mt-Ssb antibody
Anti-Mtssb antibody
Anti-Pwp1-Interacting Protein 17 antibody
Anti-SSBP1 antibody
Anti-SSBP antibody

Information sourced from Uniprot.org

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