| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SRX1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx. 16kDa band observed in Human Colon and Kidney lysates (calculated MW of 14.3kDa according to NP_542763.1). Recommended concentration: 0.5-1.5µg/ml. Primary incubation was 1 hou |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SRXN1 |
| Gene ID: | 140809 |
| Uniprot ID: | SRXN1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_542763.1 |
| Immunogen Sequence: | KVQSLVDTIREDPD |
| Function | Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. |
| Protein Name | Sulfiredoxin-1 |
| Database Links | Reactome: R-HSA-9818027 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sulfiredoxin-1 antibodyAnti-SRXN1 antibodyAnti-C20orf139 antibodyAnti-SRX antibodyAnti-SRX1 antibody |
Information sourced from Uniprot.org