| Short Description : | Rabbit polyclonal anti-Serine/arginine-rich splicing factor 7 (61-110 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SRSF7 |
| Gene ID: | 6432 |
| Uniprot ID: | SRSF7_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SFRS7 at the amino acid range 61-110 |
| Immunogen Region: | 61-110 aa |
| Specificity: | 9G8 Polyclonal Antibody detects endogenous levels of 9G8 protein. |
| Post Translational Modifications | Extensively phosphorylated on serine residues in the RS domain. |
| Function | Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway).enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific. |
| Protein Name | Serine/Arginine-Rich Splicing Factor 7Splicing Factor 9g8Splicing Factor - Arginine/Serine-Rich 7 |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Serine/Arginine-Rich Splicing Factor 7 antibodyAnti-Splicing Factor 9g8 antibodyAnti-Splicing Factor - Arginine/Serine-Rich 7 antibodyAnti-SRSF7 antibodyAnti-SFRS7 antibody |
Information sourced from Uniprot.org
