Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Serine/arginine-rich splicing factor 7 (61-110 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SRSF7 |
Gene ID: |
6432 |
Uniprot ID: |
SRSF7_HUMAN |
Immunogen Region: |
61-110 aa |
Specificity: |
9G8 Polyclonal Antibody detects endogenous levels of 9G8 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human SFRS7 at the amino acid range 61-110 |
Post Translational Modifications | Extensively phosphorylated on serine residues in the RS domain. |
Function | Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway).enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific. |
Protein Name | Serine/Arginine-Rich Splicing Factor 7Splicing Factor 9g8Splicing Factor - Arginine/Serine-Rich 7 |
Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856 |
Cellular Localisation | NucleusCytoplasm |
Alternative Antibody Names | Anti-Serine/Arginine-Rich Splicing Factor 7 antibodyAnti-Splicing Factor 9g8 antibodyAnti-Splicing Factor - Arginine/Serine-Rich 7 antibodyAnti-SRSF7 antibodyAnti-SFRS7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance