Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Serine/arginine-rich splicing factor 6 (30-110 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SRSF6 |
Gene ID: |
6431 |
Uniprot ID: |
SRSF6_HUMAN |
Immunogen Region: |
30-110 aa |
Specificity: |
SRp55 Polyclonal Antibody detects endogenous levels of SRp55 protein. |
Immunogen: |
Synthesized peptide derived from SRp55 at the amino acid range 30-110 |
Function | Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing. |
Protein Name | Serine/Arginine-Rich Splicing Factor 6Pre-Mrna-Splicing Factor Srp55Splicing Factor - Arginine/Serine-Rich 6 |
Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856 |
Cellular Localisation | NucleusNucleus Speckle |
Alternative Antibody Names | Anti-Serine/Arginine-Rich Splicing Factor 6 antibodyAnti-Pre-Mrna-Splicing Factor Srp55 antibodyAnti-Splicing Factor - Arginine/Serine-Rich 6 antibodyAnti-SRSF6 antibodyAnti-SFRS6 antibodyAnti-SRP55 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance