| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Serine/arginine-rich splicing factor 6 (30-110 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SRSF6 |
| Gene ID: | 6431 |
| Uniprot ID: | SRSF6_HUMAN |
| Immunogen Region: | 30-110 aa |
| Specificity: | SRp55 Polyclonal Antibody detects endogenous levels of SRp55 protein. |
| Immunogen: | Synthesized peptide derived from SRp55 at the amino acid range 30-110 |
| Function | Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing. |
| Protein Name | Serine/Arginine-Rich Splicing Factor 6 Pre-Mrna-Splicing Factor Srp55 Splicing Factor - Arginine/Serine-Rich 6 |
| Database Links | Reactome: R-HSA-159236 Reactome: R-HSA-72163 Reactome: R-HSA-72165 Reactome: R-HSA-72187 Reactome: R-HSA-72203 Reactome: R-HSA-73856 |
| Cellular Localisation | Nucleus Nucleus Speckle |
| Alternative Antibody Names | Anti-Serine/Arginine-Rich Splicing Factor 6 antibody Anti-Pre-Mrna-Splicing Factor Srp55 antibody Anti-Splicing Factor - Arginine/Serine-Rich 6 antibody Anti-SRSF6 antibody Anti-SFRS6 antibody Anti-SRP55 antibody |
Information sourced from Uniprot.org