• Western blot analysis of lysates from wild type (WT) and SRI knockout (KO) HeLa cells, using [KO Validated] SRI Rabbit polyclonal antibody (STJ11100797) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-SRI antibody (1-198) (STJ11100797)

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STJ11100797

£129.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SRI (1-198) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SRI
Gene ID: 6717
Uniprot ID: SORCN_HUMAN
Immunogen Region: 1-198
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SRI (NP_003121.1).
Immunogen Sequence: MAYPGHPGAGGGYYPGGYGG APGGPAFPGQTQDPLYGYFA AVAGQDGQIDADELQRCLTQ SGIAGGYKPFNLETCRLMVS MLDRDMSGTMGFNEFKELWA VLNGWRQHFISFDTDRSGTV DPQELQKALTTMGFRLSPQA VNSIAKRYSTNGKITFDDYI ACCVKLRALTDSFRRRDTAQ QGVVNFPYDDFIQCVMSV
Tissue Specificity Detected in cardiac myocytes.
Function Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Protein Name Sorcin
22 Kda Protein
Cp-22
Cp22
V19
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-418359
Reactome: R-HSA-425561
Reactome: R-HSA-5578775
Reactome: R-HSA-936837
Cellular Localisation Cytoplasm
Sarcoplasmic Reticulum Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Relocates To The Sarcoplasmic Reticulum Membrane In Response To Elevated Calcium Levels
Alternative Antibody Names Anti-Sorcin antibody
Anti-22 Kda Protein antibody
Anti-Cp-22 antibody
Anti-Cp22 antibody
Anti-V19 antibody
Anti-SRI antibody

Information sourced from Uniprot.org

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