Anti-SRD5A2 antibody [R02-2U8] (STJA0037298)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human SRD5A2
General Information
| Short Description | Rabbit monoclonal anti-SRD5A2 for use in WB and IP in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-2U8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SRD5A2 |
| Gene ID | 6716 |
| Uniprot ID | S5A2_HUMAN |
| Immunogen | A synthesized peptide derived from human SRD5A2 |
Additional Info
| Tissue Specificity | Expressed in high levels in the prostate and many other androgen-sensitive tissues. |
| Function | Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
| Protein Name | 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 25 Alpha-Sr2Sr Type 2Steroid 5-Alpha-Reductase 2S5ar 2Type Ii 5-Alpha Reductase |
| Database Links | Reactome: R-HSA-193048 |
| Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 antibodyAnti-5 Alpha-Sr2 antibodyAnti-Sr Type 2 antibodyAnti-Steroid 5-Alpha-Reductase 2 antibodyAnti-S5ar 2 antibodyAnti-Type Ii 5-Alpha Reductase antibodyAnti-SRD5A2 antibody |
Information sourced from Uniprot.org