| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SRD5A2 (190-250 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1: 4000 is recommended for WB and 1: 2000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
SRD5A2 |
| Gene ID: |
6716 |
| Uniprot ID: |
S5A2_HUMAN |
| Immunogen Region: |
190-250 aa |
| Specificity: |
Specific for SRD5A2. |
| Immunogen: |
A synthetic peptide from aa region 190-250 of human SRD5A2 conjugated to blue carrier protein was used as the antigen. |
| Function | Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
| Protein Name | 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 25 Alpha-Sr2Sr Type 2Steroid 5-Alpha-Reductase 2S5ar 2Type Ii 5-Alpha Reductase |
| Database Links | Reactome: R-HSA-193048 |
| Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 antibodyAnti-5 Alpha-Sr2 antibodyAnti-Sr Type 2 antibodyAnti-Steroid 5-Alpha-Reductase 2 antibodyAnti-S5ar 2 antibodyAnti-Type Ii 5-Alpha Reductase antibodyAnti-SRD5A2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
