| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SRD5A1 |
| Gene ID: | 6715 |
| Uniprot ID: | S5A1_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1). |
| Immunogen Sequence: | LIYPFLMRGGKPMPLLACTM AIMFCTCNGYLQSRYLSHCA VYADDWVTDPRFLIGFGLWL TGMLINIHSDHILRNLRKPG DTGYKIPRGGLFEYVTAANY F |
| Tissue Specificity | Liver and prostate (at a low level). |
| Function | Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
| Protein Name | 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 1Sr Type 1Steroid 5-Alpha-Reductase 1S5ar 1 |
| Database Links | Reactome: R-HSA-193048 |
| Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 1 antibodyAnti-Sr Type 1 antibodyAnti-Steroid 5-Alpha-Reductase 1 antibodyAnti-S5ar 1 antibodyAnti-SRD5A1 antibody |
Information sourced from Uniprot.org