Anti-SPRR1B antibody (1-89 aa) (STJ11106762)

SKU:
STJ11106762
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: SPRR1B
Gene ID: 6699
Uniprot ID: SPR1B_HUMAN
Immunogen Region: 1-89 aa
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1-89 of human SPRR1B (NP_003116.2).
Immunogen Sequence: MSSQQQKQPCTPPPQLQQQQ VKQPCQPPPQEPCIPKTKEP CHPKVPEPCHPKVPEPCQPK VPEPCHPKVPEPCPSIVTPA PAQQKTKQK
Tissue Specificity Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.
Post Translational Modifications The N-terminus is blocked.
Function Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Protein Name Cornifin-B
14.9 Kda Pancornulin
Small Proline-Rich Protein Ib
Spr-Ib
Database Links Reactome: R-HSA-6809371
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Cornifin-B antibody
Anti-14.9 Kda Pancornulin antibody
Anti-Small Proline-Rich Protein Ib antibody
Anti-Spr-Ib antibody
Anti-SPRR1B antibody

Information sourced from Uniprot.org