Tissue Specificity | Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea. |
Post Translational Modifications | The N-terminus is blocked. |
Function | Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage. |
Protein Name | Cornifin-B14.9 Kda PancornulinSmall Proline-Rich Protein IbSpr-Ib |
Database Links | Reactome: R-HSA-6809371 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Cornifin-B antibodyAnti-14.9 Kda Pancornulin antibodyAnti-Small Proline-Rich Protein Ib antibodyAnti-Spr-Ib antibodyAnti-SPRR1B antibody |
Information sourced from Uniprot.org