| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPINT1 |
| Gene ID: | 6692 |
| Uniprot ID: | SPIT1_HUMAN |
| Immunogen Region: | 234-513 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-513 of human SPINT1 (NP_003701.1). |
| Immunogen Sequence: | ANVTVTVLSTKQTEDYCLAS NKVGRCRGSFPRWYYDPTEQ ICKSFVYGGCLGNKNNYLRE EECILACRGVQGPSMERRHP VCSGTCQPTQFRCSNGCCID SFLECDDTPNCPDASDEAAC EKYTSGFDELQRIHFPSDKG HCVDLPDTGLCKESIPRWYY NPFSEHCARFTYGGCYGNKN NFEEEQQCLESCRGISKKDV FGLRREIPIPSTGSVEMAVA VFLVICIVVVVAILGYCFF |
| Function | Inhibitor of HGFAC. Inhibits serine protease activity of ST14/matriptase in vitro. Inhibits serine protease activity of TMPRSS13, via the BPTI/Kunitz inhibitor 1 domain. |
| Protein Name | Kunitz-Type Protease Inhibitor 1Hepatocyte Growth Factor Activator Inhibitor Type 1Hai-1 |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | SecretedCytoplasmCell Membrane |
| Alternative Antibody Names | Anti-Kunitz-Type Protease Inhibitor 1 antibodyAnti-Hepatocyte Growth Factor Activator Inhibitor Type 1 antibodyAnti-Hai-1 antibodyAnti-SPINT1 antibodyAnti-HAI1 antibodyAnti-UNQ223 antibodyAnti-PRO256 antibody |
Information sourced from Uniprot.org