Anti-SPINK1 antibody (24-79) (STJ115507)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SPINK1 (24-79) antibody for use in IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPINK1 |
| Gene ID | 6690 |
| Uniprot ID | ISK1_HUMAN |
| Immunogen Region | 24-79 |
| Immunogen Sequence | DSLGREAKCYNELNGCTKIY DPVCGTDGNTYPNECVLCFE NRKRQTSILIQKSGPC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-79 of human SPINK1 (NP_003113.2). |
Additional Info
| Function | Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens. In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production. |
| Protein Name | Serine Protease Inhibitor Kazal-Type 1Pancreatic Secretory Trypsin InhibitorTumor-Associated Trypsin InhibitorTati |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serine Protease Inhibitor Kazal-Type 1 antibodyAnti-Pancreatic Secretory Trypsin Inhibitor antibodyAnti-Tumor-Associated Trypsin Inhibitor antibodyAnti-Tati antibodyAnti-SPINK1 antibodyAnti-PSTI antibody |
Information sourced from Uniprot.org