| Applications: | IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPINK1 |
| Gene ID: | 6690 |
| Uniprot ID: | ISK1_HUMAN |
| Immunogen Region: | 24-79 |
| Immunogen Sequence: | DSLGREAKCYNELNGCTKIY DPVCGTDGNTYPNECVLCFE NRKRQTSILIQKSGPC |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-79 of human SPINK1 (NP_003113.2). |
| Function | Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens. In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production. |
| Protein Name | Serine Protease Inhibitor Kazal-Type 1Pancreatic Secretory Trypsin InhibitorTumor-Associated Trypsin InhibitorTati |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serine Protease Inhibitor Kazal-Type 1 antibodyAnti-Pancreatic Secretory Trypsin Inhibitor antibodyAnti-Tumor-Associated Trypsin Inhibitor antibodyAnti-Tati antibodyAnti-SPINK1 antibodyAnti-PSTI antibody |
Information sourced from Uniprot.org
