Anti-SPESP1 antibody (STJA0009378)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SPESP1
General Information
| Short Description | Rabbit polyclonal anti-Sperm equatorial segment protein 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPESP1 |
| Gene ID | 246777 |
| Uniprot ID | SPESP_HUMAN |
| Immunogen | Synthesized peptide derived from human SPESP1 |
| Specificity | This antibody detects endogenous levels of SPESP1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Glycosylated. In testis there are two predominant forms of 77- and 67-kDa and a form of 47-kDa, whereas in epididymal sperm from caput, corpus, and cauda there are two forms of 47- and 43-kDa. Testis forms contain complex carbohydrate residues. Epididymal sperm forms are N-glycosylated. Then undergoes significant glycosylation in the testis and that the majority of these glycoconjugates are removed by the time sperm reach the caput epididymis. |
| Function | Involved in fertilization ability of sperm. |
| Protein Name | Sperm Equatorial Segment Protein 1Sp-EspEquatorial Segment ProteinEspGlycosylated 38 Kda Sperm Protein C-7/8 |
| Database Links | |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleAcrosomeSmall Proacrosomal Granules (During The Golgi Phase)Enlarged Acrosomal Vesicles (During The Cap Phase)Acrosome (During The Elongating Phase)Equatorial Segment Of The Acrosome (During The Maturation Phase)After Acrosome Reaction Localizes To The Equatorial Segment Region In Both Noncapacitated And CapacitatedAcrosome-Reacted Sperm |
| Alternative Antibody Names | Anti-Sperm Equatorial Segment Protein 1 antibodyAnti-Sp-Esp antibodyAnti-Equatorial Segment Protein antibodyAnti-Esp antibodyAnti-Glycosylated 38 Kda Sperm Protein C-7/8 antibodyAnti-SPESP1 antibodyAnti-UNQ732 antibodyAnti-PRO1418 antibody |
Information sourced from Uniprot.org