| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPECC1L |
| Gene ID: | 23384 |
| Uniprot ID: | CYTSA_HUMAN |
| Immunogen Region: | 200-500 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human SPECC1L (NP_056145.4). |
| Immunogen Sequence: | LHLRNELRDMRAQLGINEDH SEGDEKSEKETIMAHQPTDV ESTLLQLQEQNTAIREELNQ LKNENRMLKDRLNALGFSLE QRLDNSEKLFGYQSLSPEIT PGNQSDGGGTLTSSVEGSAP GSVEDLLSQDENTLMDHQHS NSMDNLDSECSEVYQPLTSS DDALDAPSSSESEGIPSIER SRKGSSGNASEVSVACLTER IHQMEENQHSTSEELQATLQ ELADLQQITQELNSENERL |
| Function | Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration. |
| Protein Name | Cytospin-ARenal Carcinoma Antigen Ny-Ren-22Sperm Antigen With Calponin Homology And Coiled-Coil Domains 1-LikeSpecc1-Like Protein |
| Cellular Localisation | CytoplasmCytoskeletonSpindleCell JunctionGap JunctionColocalizes With Acetylated Alpha-TubulinGamma-Tubulin And F-ActinAlso Observed In A Ring Around Gamma-Tubulin Containing Centrioles Possibly In The Microtubule Organizing Center |
| Alternative Antibody Names | Anti-Cytospin-A antibodyAnti-Renal Carcinoma Antigen Ny-Ren-22 antibodyAnti-Sperm Antigen With Calponin Homology And Coiled-Coil Domains 1-Like antibodyAnti-Specc1-Like Protein antibodyAnti-SPECC1L antibodyAnti-CYTSA antibodyAnti-KIAA0376 antibody |
Information sourced from Uniprot.org