Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-SPA1/SIPA1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
ELISA-antibody detection limit dilution 1:32000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
SIPA1 |
Gene ID: |
6494 |
Uniprot ID: |
SIPA1_HUMAN |
Immunogen Region: |
C-Term |
Accession Number: |
NP_694985.28; NP_006738.3 |
Specificity: |
Both variants represent identical protein (NP_694985.28 and NP_006738.3). |
Immunogen Sequence: |
ASKQLGSPTADLA |
Function | GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state. Affects cell cycle progression. |
Protein Name | Signal-Induced Proliferation-Associated Protein 1Sipa-1Gtpase-Activating Protein Spa-1P130 Spa-1 |
Database Links | Reactome: R-HSA-392517 |
Cellular Localisation | NucleusCytoplasmPerinuclear RegionEndomembrane SystemPeripheral Membrane ProteinMostly Localized In The Perinuclear Membraneous Region |
Alternative Antibody Names | Anti-Signal-Induced Proliferation-Associated Protein 1 antibodyAnti-Sipa-1 antibodyAnti-Gtpase-Activating Protein Spa-1 antibodyAnti-P130 Spa-1 antibodyAnti-SIPA1 antibodyAnti-SPA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance