Anti-SOX2 antibody (50-100) {Biotin} (STJ503094)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 50-100Β on human Sex determing region Y-box 2 protein.
STJ503094-100
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General Information

Short DescriptionRabbit polyclonal antibody anti-SOX2 (50-100) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
ApplicationsELISA/IP/WB
HostRabbit
ReactivityHuman/Monkey/Mouse/Pig
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationBiotin
Concentration0.55-0.75 Β΅g/Β΅l
PurificationAffinity Purified
Dilution RangeWB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:150
IHC: 1:50-1:150
FormulationContains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage InstructionStore at-20Β°C for long term storage. Avoid freeze-thaw cycles.

Target Information

ImmunogenSynthetic peptide taken within amino acid region 50-100Β on human Sex determing region Y-box 2 protein.
Immunogen Region50-100

Additional Info

Background Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.

Information sourced from Uniprot.org

Citations

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