Anti-SOX-11 antibody [MRQ-58] (STJ16100461)

Anti-SOX-11 antibody [MRQ-58] (STJ16100461)

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STJ16100461
£1,167.50 - £1,853.50
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-SOX-11 is suitable for use in Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : MRQ-58
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Dilution Range: IHC 1:25 – 1:100
Storage Instruction: Store at 2-8°C upon receipt.
Background SOX-11 which is a member of the SOX (SRY-related HMG-box) family is a transcription factor normally expressed in the developing human central nervous system and plays a role in embryonic cell determination. Studies show that SOX-11 can be used as a marker for mantle cell lymphoma (MCL). Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of cyclin D1 (CCND1) , an important regulator of the G1/S phase of the cell cycle, due to the specific translocation t (11;14) (q13;q32).

Information sourced from Uniprot.org

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