| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SOST (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.IHC: In paraffin embedded Human Kidney shows cytoplasm staining exclusively in the PCT. Recommended concentration: 4-6µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SOST |
| Gene ID: | 50964 |
| Uniprot ID: | SOST_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_079513.1 |
| Immunogen Sequence: | PRARSAKANQAELEN |
| Function | Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. |
| Protein Name | Sclerostin |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Sclerostin antibodyAnti-SOST antibodyAnti-UNQ2976 antibodyAnti-PRO7455 antibodyAnti-PRO7476 antibody |
Information sourced from Uniprot.org
