| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-SORCS3 (C-Term) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SORCS3 |
| Gene ID: | 22986 |
| Uniprot ID: | SORC3_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | Specific for SORCS3. |
| Immunogen: | A synthetic peptide from the c-terminal region of human SORCS3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with mouse sequence. |
| Function | Plays an important role in modulating synaptic transmission and plasticity in the hippocampus, probably by affecting the trafficking and localization ofAMPA-type glutamate receptors in the postsynaptic density. |
| Protein Name | Vps10 Domain-Containing Receptor Sorcs3 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynaptic Cell MembranePostsynaptic Density |
| Alternative Antibody Names | Anti-Vps10 Domain-Containing Receptor Sorcs3 antibodyAnti-SORCS3 antibodyAnti-KIAA1059 antibody |
Information sourced from Uniprot.org
