| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SOD3 |
| Gene ID: | 6649 |
| Uniprot ID: | SODE_HUMAN |
| Immunogen Region: | 19-160 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 19-160 of human SOD3 (NP_003093.2). |
| Immunogen Sequence: | WTGEDSAEPNSDSAEWIRDM YAKVTEIWQEVMQRRDDDGA LHAACQVQPSATLDAAQPRV TGVVLFRQLAPRAKLDAFFA LEGFPTEPNSSSRAIHVHQF GDLSQGCESTGPHYNPLAVP HPQHPGDFGNFAVRDGSLWR YR |
| Tissue Specificity | Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid. |
| Function | Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. |
| Protein Name | Extracellular Superoxide Dismutase Cu-ZnEc-Sod |
| Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-9818027 |
| Cellular Localisation | SecretedExtracellular SpaceGolgi ApparatusTrans-Golgi Network99% Of Ec-Sod Is Anchored To Heparan Sulfate Proteoglycans In The Tissue InterstitiumAnd 1% Is Located In The Vasculature In Equilibrium Between The Plasma And The Endothelium |
| Alternative Antibody Names | Anti-Extracellular Superoxide Dismutase Cu-Zn antibodyAnti-Ec-Sod antibodyAnti-SOD3 antibody |
Information sourced from Uniprot.org