| Short Description : | Goat polyclonal antibody anti-SNX5 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IHC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx. 48kDa band observed in Jurkat and A549 lysates (calculated MW of 46.8kDa according to NP_055241.1). Recommended concentration: 1-3µg/ml. Primary incubation was one hour.IH |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SNX5 |
| Gene ID: | 27131 |
| Uniprot ID: | SNX5_HUMAN |
| Accession Number: | NP_055241.1; NP_001269383.1 |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | SLLQSCIDLFKNN |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_055241.1; NP_001269383.1). Reported variants represent identical protein: NP_055241.1, NP_689413.1 |
| Protein Name | Sorting Nexin-5 |
| Database Links | Reactome: R-HSA-432722 |
| Cellular Localisation | EndosomeEarly EndosomeEarly Endosome MembranePeripheral Membrane ProteinCytoplasmic SideCell MembraneCytoplasmic Vesicle MembraneCytoplasmCell ProjectionPhagocytic CupRuffleRecruited To The Plasma Membrane After Egf StimulationWhich Leads To Increased Levels Of Phosphatidylinositol 34-Bisphosphate (Pdtins(34)P2)Detected On MacropinosomesTargeted To Membrane Ruffles In Response To Egfr Stimulation |
| Alternative Antibody Names | Anti-Sorting Nexin-5 antibodyAnti-SNX5 antibody |
Information sourced from Uniprot.org
