| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SNX16 (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 38kDa band observed in lysates of cell line Daudi (calculated MW of 39.2kDa according to NP_071416.2). In transfected HEK293 transiently expressing SNX16 a band of approx. 40kDa |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SNX16 |
| Gene ID: | 64089 |
| Uniprot ID: | SNX16_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_071416.2; NP_690049.1; NP_690050.1 |
| Specificity: | This antibody is expected to recognise both isoform a (NP_071416.2; NP_690049.1) and isoform b (NP_690050.1). |
| Immunogen Sequence: | ATPYVPVPMPIGN |
| Function | May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm. |
| Protein Name | Sorting Nexin-16 |
| Cellular Localisation | Early Endosome MembranePeripheral Membrane ProteinCytoplasmic SideLate Endosome MembraneCytoplasmLysosome |
| Alternative Antibody Names | Anti-Sorting Nexin-16 antibodyAnti-SNX16 antibody |
Information sourced from Uniprot.org
