Anti-SNTA1 antibody (289-339 aa) (STJ194962)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SNTA1 at the amino acid range 289-339
General Information
| Short Description | Rabbit polyclonal anti-Alpha-1-syntrophin (289-339 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SNTA1 |
| Gene ID | 6640 |
| Uniprot ID | SNTA1_HUMAN |
| Immunogen | Synthesized peptide derived from the human SNTA1 at the amino acid range 289-339 |
| Immunogen Region | 289-339 aa |
| Specificity | This antibody detects endogenous levels of SNTA1 at Human/Mouse |
Additional Info
| Post Translational Modifications | Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD. |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate. |
| Protein Name | Alpha-1-Syntrophin59 Kda Dystrophin-Associated Protein A1 Acidic Component 1Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1Tacip1Syntrophin-1 |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic SideCell JunctionCytoplasmCytoskeletonIn Skeletal MuscleIt Localizes At The Cytoplasmic Side Of The Sarcolemmal Membrane And At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Alpha-1-Syntrophin antibodyAnti-59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 antibodyAnti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 antibodyAnti-Tacip1 antibodyAnti-Syntrophin-1 antibodyAnti-SNTA1 antibodyAnti-SNT1 antibody |
Information sourced from Uniprot.org