| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Alpha-1-syntrophin (289-339 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SNTA1 |
| Gene ID: | 6640 |
| Uniprot ID: | SNTA1_HUMAN |
| Immunogen Region: | 289-339 aa |
| Specificity: | This antibody detects endogenous levels of SNTA1 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human SNTA1 at the amino acid range 289-339 |
| Post Translational Modifications | Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD. |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate. |
| Protein Name | Alpha-1-Syntrophin 59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 Tacip1 Syntrophin-1 |
| Cellular Localisation | Cell Membrane Sarcolemma Peripheral Membrane Protein Cytoplasmic Side Cell Junction Cytoplasm Cytoskeleton In Skeletal Muscle It Localizes At The Cytoplasmic Side Of The Sarcolemmal Membrane And At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Alpha-1-Syntrophin antibody Anti-59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 antibody Anti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 antibody Anti-Tacip1 antibody Anti-Syntrophin-1 antibody Anti-SNTA1 antibody Anti-SNT1 antibody |
Information sourced from Uniprot.org
