| Post Translational Modifications | Methylated on arginine residues by PRMT5 and PRMT7.probable asymmetric dimethylation which is required for assembly and biogenesis of snRNPs. |
| Function | Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. |
| Protein Name | Small Nuclear Ribonucleoprotein Sm D3Sm-D3Snrnp Core Protein D3 |
| Database Links | Reactome: R-HSA-111367Reactome: R-HSA-191859Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-73856Reactome: R-HSA-77588Reactome: R-HSA-9754678 |
| Cellular Localisation | CytoplasmCytosolNucleusSmn-Mediated Assembly Into Core Snrnps Occurs In The Cytosol Before Smn-Mediated Transport To The Nucleus To Be Included In Spliceosomes |
| Alternative Antibody Names | Anti-Small Nuclear Ribonucleoprotein Sm D3 antibodyAnti-Sm-D3 antibodyAnti-Snrnp Core Protein D3 antibodyAnti-SNRPD3 antibody |
Information sourced from Uniprot.org
