| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Small nuclear ribonucleoprotein-associated proteins B and B NA (42-92 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SNRPB |
| Gene ID: |
6628 |
| Uniprot ID: |
RSMB_HUMAN |
| Immunogen Region: |
42-92 aa |
| Specificity: |
This antibody detects endogenous levels of RSMB at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human RSMB at the amino acid range 42-92 |
| Function | Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. |
| Protein Name | Small Nuclear Ribonucleoprotein-Associated Proteins B And B'Snrnp-BSm Protein B/B'Sm-B/B'Smb/B' |
| Database Links | Reactome: R-HSA-111367Reactome: R-HSA-191859Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-73856Reactome: R-HSA-77588Reactome: R-HSA-9754678 |
| Cellular Localisation | CytoplasmCytosolNucleusSmn-Mediated Assembly Into Core Snrnps Occurs In The Cytosol Before Smn-Mediated Transport To The Nucleus To Be Included In Spliceosomes |
| Alternative Antibody Names | Anti-Small Nuclear Ribonucleoprotein-Associated Proteins B And B' antibodyAnti-Snrnp-B antibodyAnti-Sm Protein B/B' antibodyAnti-Sm-B/B' antibodyAnti-Smb/B' antibodyAnti-SNRPB antibodyAnti-COD antibodyAnti-SNRPB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
