| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SNRNP40 |
| Gene ID: | 9410 |
| Uniprot ID: | SNR40_HUMAN |
| Immunogen Region: | 1-357 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-357 of human SNRNP40 (NP_004805.2). |
| Immunogen Sequence: | MIEQQKRKGPELPLVPVKRQ RHELLLGAGSGPGAGQQQAT PGALLQAGPPRCSSLQAPIM LLSGHEGEVYCCKFHPNGST LASAGFDRLILLWNVYGDCD NYATLKGHSGAVMELHYNTD GSMLFSASTDKTVAVWDSET GERVKRLKGHTSFVNSCYPA RRGPQLVCTGSDDGTVKLWD IRKKAAIQTFQNTYQVLAVT FNDTSDQIISGGIDNDIKVW DLRQNKLTYTMRGHADSVT |
| Function | Required for pre-mRNA splicing as component of the activated spliceosome. Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Protein Name | U5 Small Nuclear Ribonucleoprotein 40 Kda ProteinU5 Snrnp 40 Kda ProteinU5-40k38 Kda-Splicing FactorPrp8-Binding ProteinHprp8bpU5 Snrnp-Specific 40 Kda ProteinWd Repeat-Containing Protein 57 |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-U5 Small Nuclear Ribonucleoprotein 40 Kda Protein antibodyAnti-U5 Snrnp 40 Kda Protein antibodyAnti-U5-40k antibodyAnti-38 Kda-Splicing Factor antibodyAnti-Prp8-Binding Protein antibodyAnti-Hprp8bp antibodyAnti-U5 Snrnp-Specific 40 Kda Protein antibodyAnti-Wd Repeat-Containing Protein 57 antibodyAnti-SNRNP40 antibodyAnti-PRP8BP antibodyAnti-SFP38 antibodyAnti-WDR57 antibody |
Information sourced from Uniprot.org