| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SNRNP200 (1947-2136) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SNRNP200 |
| Gene ID: |
23020 |
| Uniprot ID: |
U520_HUMAN |
| Immunogen Region: |
1947-2136 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2). |
| Immunogen Sequence: |
QMVTQAMWSKDSYLKQLPHF TSEHIKRCTDKGVESVFDIM EMEDEERNALLQLTDSQIAD VARFCNRYPNIELSYEVVDK DSIRSGGPVVVLVQLEREEE VTGPVIAPLFPQKREEGWWV VIGDAKSNSLISIKRLTLQQ KAKVKLDFVAPATGAHNYTL YFMSDAYMGCDQEYKFSVDV KEAETDSDSD |
| Tissue Specificity | Widely expressed. |
| Function | Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. Plays a role in pre-mRNA splicing as a core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. |
| Protein Name | U5 Small Nuclear Ribonucleoprotein 200 Kda HelicaseActivating Signal Cointegrator 1 Complex Subunit 3-Like 1Brr2 HomologU5 Snrnp-Specific 200 Kda ProteinU5-200kd |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-U5 Small Nuclear Ribonucleoprotein 200 Kda Helicase antibodyAnti-Activating Signal Cointegrator 1 Complex Subunit 3-Like 1 antibodyAnti-Brr2 Homolog antibodyAnti-U5 Snrnp-Specific 200 Kda Protein antibodyAnti-U5-200kd antibodyAnti-SNRNP200 antibodyAnti-ASCC3L1 antibodyAnti-BRR2 antibodyAnti-HELIC2 antibodyAnti-KIAA0788 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
