| Tissue Specificity | Widely expressed. |
| Function | Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. Plays a role in pre-mRNA splicing as a core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. |
| Protein Name | U5 Small Nuclear Ribonucleoprotein 200 Kda HelicaseActivating Signal Cointegrator 1 Complex Subunit 3-Like 1Brr2 HomologU5 Snrnp-Specific 200 Kda ProteinU5-200kd |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-U5 Small Nuclear Ribonucleoprotein 200 Kda Helicase antibodyAnti-Activating Signal Cointegrator 1 Complex Subunit 3-Like 1 antibodyAnti-Brr2 Homolog antibodyAnti-U5 Snrnp-Specific 200 Kda Protein antibodyAnti-U5-200kd antibodyAnti-SNRNP200 antibodyAnti-ASCC3L1 antibodyAnti-BRR2 antibodyAnti-HELIC2 antibodyAnti-KIAA0788 antibody |
Information sourced from Uniprot.org
