| Short Description : | Rabbit polyclonal SNAP91 (321-600) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SNAP91 |
| Gene ID: | 9892 |
| Uniprot ID: | AP180_HUMAN |
| Immunogen Region: | 321-600 |
| Immunogen Sequence: | AVPVSTSKPSSDLLDLQPDF SSGGAAAAAAPAPPPPAGGA TAWGGFGGSFMAPSPSPVTP AQNNLLQPNFEAAFGTTPST SSSSSFDPSVFDGLGDLLMP TMAPAGQPAPVSMVPPSPAM AASKALGSDLDSSLASLVGN LGISGTTTKKGDLQWNAGEK KLTGGANWQPKVAPATWSAG VPPSAPLQGAVPPTSSVPPV AGAPSVGQPGAGFGMPPAGT GMPMMPQQPVMFAQPMMRP |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human SNAP91 (NP_001229723.1). |
| Post Translational Modifications | Thr-310 can be modified by the addition of N-acetylglucosamine which can be further phosphorylated. There is no evidence for direct Thr-310 phosphorylation. |
| Function | Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats. |
| Protein Name | Clathrin Coat Assembly Protein Ap18091 Kda Synaptosomal-Associated ProteinClathrin Coat-Associated Protein Ap180Phosphoprotein F1-20 |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMembraneCoated PitPeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles In The Plasma Membrane |
| Alternative Antibody Names | Anti-Clathrin Coat Assembly Protein Ap180 antibodyAnti-91 Kda Synaptosomal-Associated Protein antibodyAnti-Clathrin Coat-Associated Protein Ap180 antibodyAnti-Phosphoprotein F1-20 antibodyAnti-SNAP91 antibodyAnti-KIAA0656 antibody |
Information sourced from Uniprot.org
