| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SNAP91 (321-600) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SNAP91 |
| Gene ID: |
9892 |
| Uniprot ID: |
AP180_HUMAN |
| Immunogen Region: |
321-600 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human SNAP91 (NP_001229723.1). |
| Immunogen Sequence: |
AVPVSTSKPSSDLLDLQPDF SSGGAAAAAAPAPPPPAGGA TAWGGFGGSFMAPSPSPVTP AQNNLLQPNFEAAFGTTPST SSSSSFDPSVFDGLGDLLMP TMAPAGQPAPVSMVPPSPAM AASKALGSDLDSSLASLVGN LGISGTTTKKGDLQWNAGEK KLTGGANWQPKVAPATWSAG VPPSAPLQGAVPPTSSVPPV AGAPSVGQPGAGFGMPPAGT GMPMMPQQPVMFAQPMMRP |
| Post Translational Modifications | Thr-310 can be modified by the addition of N-acetylglucosamine which can be further phosphorylated. There is no evidence for direct Thr-310 phosphorylation. |
| Function | Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats. |
| Protein Name | Clathrin Coat Assembly Protein Ap18091 Kda Synaptosomal-Associated ProteinClathrin Coat-Associated Protein Ap180Phosphoprotein F1-20 |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMembraneCoated PitPeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles In The Plasma Membrane |
| Alternative Antibody Names | Anti-Clathrin Coat Assembly Protein Ap180 antibodyAnti-91 Kda Synaptosomal-Associated Protein antibodyAnti-Clathrin Coat-Associated Protein Ap180 antibodyAnti-Phosphoprotein F1-20 antibodyAnti-SNAP91 antibodyAnti-KIAA0656 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
