| Tissue Specificity | Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas. |
| Function | Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Also methylates 'Lys-5' of histone H4. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. |
| Protein Name | Histone-Lysine N-Methyltransferase Smyd3Set And Mynd Domain-Containing Protein 3Zinc Finger Mynd Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | CytoplasmNucleusMainly Cytoplasmic When Cells Are Arrested At G0/G1Accumulates In The Nucleus At S Phase And G2/M |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Smyd3 antibodyAnti-Set And Mynd Domain-Containing Protein 3 antibodyAnti-Zinc Finger Mynd Domain-Containing Protein 1 antibodyAnti-SMYD3 antibodyAnti-ZMYND1 antibodyAnti-ZNFN3A1 antibody |
Information sourced from Uniprot.org
