| Host: | Mouse |
| Applications: | WB |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Histone-lysine N-methyltransferase SMYD1 is suitable for use in Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 2E11-B6-C7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SMYD1 |
| Gene ID: | 150572 |
| Uniprot ID: | SMYD1_HUMAN |
| Specificity: | This antibody detects endogenous levels of SMYD1 and does not cross-react with related proteins. |
| Immunogen: | Purified recombinant human SMYD1 protein fragments expressed in E.coli. |
| Function | Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. |
| Protein Name | Histone-Lysine N-Methyltransferase Smyd1Set And Mynd Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-9733709 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Smyd1 antibodyAnti-Set And Mynd Domain-Containing Protein 1 antibodyAnti-SMYD1 antibody |
Information sourced from Uniprot.org