| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SMS |
| Gene ID: | 6611 |
| Uniprot ID: | SPSY_HUMAN |
| Immunogen Region: | 1-366 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-366 of human SMS (NP_004586.2). |
| Immunogen Sequence: | MAAARHSTLDFMLGAKADGE TILKGLQSIFQEQGMAESVH TWQDHGYLATYTNKNGSFAN LRIYPHGLVLLDLQSYDGDA QGKEEIDSILNKVEERMKEL SQDSTGRVKRLPPIVRGGAI DRYWPTADGRLVEYDIDEVV YDEDSPYQNIKILHSKQFGN ILILSGDVNLAESDLAYTRA IMGSGKEDYTGKDVLILGGG DGGILCEIVKLKPKMVTMVE IDQMVIDGCKKYMRKTCGD |
| Function | Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM). |
| Protein Name | Spermine SynthaseSpmsySpermidine Aminopropyltransferase |
| Database Links | Reactome: R-HSA-351202 |
| Alternative Antibody Names | Anti-Spermine Synthase antibodyAnti-Spmsy antibodyAnti-Spermidine Aminopropyltransferase antibodyAnti-SMS antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and SETD7 knockout (KO) 293T cells, using [KO Validated] SETD7 Rabbit pAb (STJ112026) at 1:1000 dilution. <br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. <br/>Lysates/proteins: 25 Mu g per lane. <br/>Blocking buffer: 3% nonfat dry milk in TBST. <br/>Detection: ECL Basic Kit <br/>Exposure time: 60s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/92100/409178/STJ112026_1__61044.1744895598.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and SETD7 knockout (KO) 293T cells, using [KO Validated] SETD7 Rabbit pAb (STJ112026) at 1:1000 dilution. <br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. <br/>Lysates/proteins: 25 Mu g per lane. <br/>Blocking buffer: 3% nonfat dry milk in TBST. <br/>Detection: ECL Basic Kit <br/>Exposure time: 60s.")
