Anti-SMARCAD1 antibody (STJ191928)

SKU:
STJ191928
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
ELISA 1:5000-20000
Formulation:Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SMARCAD1
Gene ID:56916
Uniprot ID:SMRCD_HUMAN
Immunogen:Synthesized peptide derived from part of the human protein
Specificity:SMRCD Polyclonal Antibody detects endogenous levels of protein.
Function DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs. Required for the restoration of heterochromatin organization after replication. Acts at replication sites to facilitate the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3 'Lys-9' trimethylation (H3K9me3) and restoration of silencing.
Protein Name Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Containing Dead/H Box 1
Smarcad1
Atp-Dependent Helicase 1
Hhel1
Database Links
Cellular Localisation Nucleus
Chromosome
Colocalizes With Pcna At Replication Forks During S Phase
Recruited To Double-Strand Breaks (Dsbs) Sites Of Dna Damage
Alternative Antibody Names Anti-Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Containing Dead/H Box 1 antibody
Anti-Smarcad1 antibody
Anti-Atp-Dependent Helicase 1 antibody
Anti-Hhel1 antibody
Anti-SMARCAD1 antibody
Anti-KIAA1122 antibody

Information sourced from Uniprot.org

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