Anti-SMAD9 antibody (1-300) (STJ29654)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SMAD9 (1-300) antibody for use in IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SMAD9 |
| Gene ID | 4093 |
| Uniprot ID | SMAD9_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MHSTTPISSLFSFTSPAVKR LLGWKQGDEEEKWAEKAVDS LVKKLKKKKGAMDELERALS CPGQPSKCVTIPRSLDGRLQ VSHRKGLPHVIYCRVWRWPD LQSHHELKPLECCEFPFGSK QKEVCINPYHYRRVETPVLP PVLVPRHSEYNPQLSLLAKF RSASLHSEPLMPHNATYPDS FQQPPCSALPPSPSHAFSQS PCTASYPHSPGSPSEPESPY QHSDFRPVCYEEPQHWCSV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Smad9 (NP_005896.1). |
Additional Info
| Tissue Specificity | Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney. |
| Post Translational Modifications | Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase. |
| Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). |
| Protein Name | Mothers Against Decapentaplegic Homolog 9Mad Homolog 9Mothers Against Dpp Homolog 9Madh6Smad Family Member 9Smad 9Smad9 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | CytoplasmNucleusIn The Cytoplasm In The Absence Of LigandMigration To The Nucleus When Complexed With Smad4 |
| Alternative Antibody Names | Anti-Mothers Against Decapentaplegic Homolog 9 antibodyAnti-Mad Homolog 9 antibodyAnti-Mothers Against Dpp Homolog 9 antibodyAnti-Madh6 antibodyAnti-Smad Family Member 9 antibodyAnti-Smad 9 antibodyAnti-Smad9 antibodyAnti-SMAD9 antibodyAnti-MADH6 antibodyAnti-MADH9 antibodyAnti-SMAD8 antibody |
Information sourced from Uniprot.org