| Host: | Rabbit |
| Applications: | IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SMAD9 |
| Gene ID: | 4093 |
| Uniprot ID: | SMAD9_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Smad9 (NP_005896.1). |
| Immunogen Sequence: | MHSTTPISSLFSFTSPAVKR LLGWKQGDEEEKWAEKAVDS LVKKLKKKKGAMDELERALS CPGQPSKCVTIPRSLDGRLQ VSHRKGLPHVIYCRVWRWPD LQSHHELKPLECCEFPFGSK QKEVCINPYHYRRVETPVLP PVLVPRHSEYNPQLSLLAKF RSASLHSEPLMPHNATYPDS FQQPPCSALPPSPSHAFSQS PCTASYPHSPGSPSEPESPY QHSDFRPVCYEEPQHWCSV |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney. |
| Post Translational Modifications | Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase. |
| Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). |
| Protein Name | Mothers Against Decapentaplegic Homolog 9Mad Homolog 9Mothers Against Dpp Homolog 9Madh6Smad Family Member 9Smad 9Smad9 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | CytoplasmNucleusIn The Cytoplasm In The Absence Of LigandMigration To The Nucleus When Complexed With Smad4 |
| Alternative Antibody Names | Anti-Mothers Against Decapentaplegic Homolog 9 antibodyAnti-Mad Homolog 9 antibodyAnti-Mothers Against Dpp Homolog 9 antibodyAnti-Madh6 antibodyAnti-Smad Family Member 9 antibodyAnti-Smad 9 antibodyAnti-Smad9 antibodyAnti-SMAD9 antibodyAnti-MADH6 antibodyAnti-MADH9 antibodyAnti-SMAD8 antibody |
Information sourced from Uniprot.org
