Anti-SLC9A3 antibody (590-640) {Biotin} (STJ506228)

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STJ506228-100
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-SLC9A3 (590-640) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Biotin
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.5-1.5 Mu g/Mu l
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:100
ICC: 1:50-1:100
IF: 1:50-1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC9A3
Gene ID: 6550
Uniprot ID: SL9A3_HUMAN
Immunogen Region: 590-640
Immunogen: Synthetic peptide corresponding to amino acids within region 590-640 on human SLC9A3 protein.
Function Plasma membrane Na(+)/H(+) antiporter. Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis. Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation.
Protein Name Sodium/Hydrogen Exchanger 3
Na(+/H(+ Exchanger 3
Nhe-3
Solute Carrier Family 9 Member 3
Database Links Reactome: R-HSA-425986
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Recycling Endosome Membrane
Early Endosome Membrane
In Intestinal Epithelial Cells
Localizes To The Ileal Brush Border
Phosphorylation At Ser-663 By Sgk1 Is Associated With Increased Abundance At The Cell Membrane
Angiotensin-2 Enhances Apical Expression
Alternative Antibody Names Anti-Sodium/Hydrogen Exchanger 3 antibody
Anti-Na(+/H(+ Exchanger 3 antibody
Anti-Nhe-3 antibody
Anti-Solute Carrier Family 9 Member 3 antibody
Anti-SLC9A3 antibody
Anti-NHE3 antibody

Information sourced from Uniprot.org

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